This image is of two Hopi Indians looking across the Grand Canyon towards the north, from the lookout known as Hopi Point.

The description states:
HOTELS – SHOPS
FRED HARVEY
RESTAURANTS
Most of the stories told of what people have said upon catching their first glimpse of the Grand Canyon are unbelievable until you see the mighty chasm for yourself, for only then do you realize its breath-taking immensity.
–This seemingly remote location is in fact only about 2 miles from the tourist lodges on the South Rim, and a bus provides access to this and several other similar vantage points.
This card was used and is dated 21 Jun 1948.