This image features the Federal Building in Cincinnati, Ohio as it looked in the 1940s. This building also housed the main Post Office for Cincinnati at the time.
There is no description on the back of this card.
As best can be determined, this building no longer exists, and the post office has moved to a different location as a result. The cars present in the image clearly point to the image being from the 1940s. The card itself was used, and is dated February 14, 1950.